Leucine-rich repeat

The leucine-rich repeat (LRR) proteins are a large family of over 60,000 proteins found in viruses, bacteria, archaea, and eukaryotes that feature horseshoe- or arc-shaped domains made of leucine-rich repeating motifs. Presently, at least 144 structures with leucine-rich repeats are deposited at the RCSB Protein Data Bank.



Articles in Proteopedia concerning Leucine-rich repeat proteins include:
 * Human Follicle-Stimulating Hormone Complexed with its Receptor
 * Variable Lymphocyte Receptors
 * Lamprey Variable Lymphocyte Receptor
 * Leucine-rich repeat domain of Thyroid-Stimulating Hormone
 * Toll-like receptors (TLRs), such as Mouse Toll-like receptor bound to dsRNA
 * Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
 * Lingo-1 protein involved in inhibiting effective regrowth of axons after central nervous system damage

To view automatically seeded indices concerning Leucine-rich repeat proteins, see:
 * Leucine-rich repeat
 * Leucine-rich-repeat
 * Leucine-rich repeat-containing protein 4
 * LRR
 * Leucine-rich repeat glycoprotein

External Resources

 * LRRML: a conformational database and an XML description of leucine-rich repeats (LRRs)
 * TOLLML Database: database of toll-like receptor structural motifs
 * Web-Based Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors site features coverage of the ectodomain which hosts a series of leucine-rich repeats